Progranulin is an 88kDa protein and is established as a marker for frontotemporal dementia (FTD); decreased serum progranulin concentrations occur in approximately 5-10% of patients with FTD. In contrast, an increase in serum progranulin levels has been demonstrated in type 2 diabetics. Progranulin seems to reflect the distribution of adipose tissue and could be a biomarker for the amount of visceral adipose tissue.

The Mediagnost Progranulin ELISA is an assay with good reproducibility that detects progranulin and not granulins with high specificity.

 

Progranulin ELISA
Product number

E103

Regulatory status

RUO

Reference material recombinant progranulin
Incubation period 2h
Antibody Mouse
Standard recombinant progranulin
Assay Range
[µg/L]
0,018 – 103
Samples

Serum
EDTA / heparin / citrate plasma

Sample dilution 1:41
analyt. Sensitivity
[µg/L]
0,018
Intra-/Interassay Variance [%] <10
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