Hepatitis A Virus (HAV)
Diagnosis of acute HAV infection is performed by determination of specific IgM antibodies in serum by ELISA, or detection of antigen by ELISA in stool and/or serum or HAV RNA by reverse transcription polymerase chain reaction (RT-PCR) in stool and/or serum. The detection of IgG antibodies in serum indicates a past infection or an immune response after vaccination.
Since its foundation, Mediagnost has been producing the Hepatitis A virus and its monoclonal antibody for the production of own test systems as well as raw materials for diagnostic companies and offers test systems for the detection of anti-HAV antibodies (IgM and total Ig), HAV antigen and HAV RNA an.
Mediagnost has developed a test system for the detection of Antibodies against Pseudomonas aeruginosa antigens has been developed. Complementary to classical microbiology, the test detects Pseudomonas aeruginosa infections in patients with cystic fibrosis.
In the area of enteroviruses, Mediagnost has developed a highly specific monoclonal antibody which can be used to detect coxsackievirus B3 in various assays, such as immunohistology (kerosene), immunofluorescence, Western blot, FACS and ELISA.