Growth hormone and IGF
Insulin-like growth factors (IGF)-I and-II play a key role in the regulation of proliferation, differentiation and specific functions of many cell types. IGF-I has a molecular weight of 7649 daltons is substantially regulated by growth hormone, although its synthesis in specific tissues is influenced by a variety of troper hormones and other peptide growth factors. Unlike many other peptide hormones, IGFs with high affinity for specific Binding proteins (IGFBP) bound.
Mediagnost offers test system for the quantitative determination of IGF-I, IGF-II, IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-6 as well as for the measurement of the Growth hormone and its binding protein (GHBP).
Fat cells are more than just an energy store of the human body. Rather, adipose tissue is an active endocrinological organ whose hormones influence and control food intake and utilization in a variety of ways. These regulatory circuits can be disturbed by obesity, for example, and thus contribute to the development of diabetes, cardiovascular diseases or tumor diseases. Mediagnost offers test systems for the quantitative determination of Leptin and Adiponectin and a number of other adipokines such as Resistin, Vaspin, Chemerin and Progranulin an.
Mediagnost develops, produces and distributes endocrinological test systems for clinical diagnostics and research applications. In this context, Mediagnost also offers test systems with Cross-reactivity to animal hormones as well as special, animal-specific tests for measurement in mouse/rat samples for the detection of Adiponectin, IGF-I, IGFBP-2, IGFBP-3, Leptin and Growth hormone.