{"id":3131,"date":"2017-04-19T14:28:24","date_gmt":"2017-04-19T12:28:24","guid":{"rendered":"https:\/\/mediagnost.de\/?page_id=3131"},"modified":"2023-12-13T23:51:53","modified_gmt":"2023-12-13T22:51:53","slug":"leptin-human-2","status":"publish","type":"page","link":"https:\/\/mediagnost.de\/en\/leptin-human-2\/","title":{"rendered":"Leptin human"},"content":{"rendered":"

Leptin is a hormone of adipose tissue and is mainly synthesized by adipocytes. It consists of 167 amino acids and has a molecular weight of 18.64 kDa. Leptin is involved in the regulation of food intake. The concentration of leptin in the circulation is essentially determined by the body fat mass.<\/p>\n

Mediagnost offers you three different leptin tests, which differ in sensitivity, measuring range and duration. Furthermore we offer you with the b<\/a><\/span>ioLEP ELISA<\/span> <\/a>a test for the measurement of biologically active leptin<\/span><\/span><\/a>Here, the measurement is not based on two specific antibodies, but on the combination of a specific, polyclonal anit leptin antibody with the Leptin binding protein,<\/a><\/span> the extracellular part of the leptin receptor. In this way, the test allows to measure only the functional leptin that is able to bind to the receptor. As well as an sLEP-R ELISA for the quantitative determination of human soluble leptin receptor (sLEP-R),\u00a0 Product number R07<\/a>.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\nbioLEP ELISA<\/strong><\/span><\/td>\nELISA<\/strong><\/span><\/td>\nSensitive<\/strong><\/span>
\nELISA<\/strong><\/span><\/td>\n		RIA-CT<\/strong><\/span><\/td>\n<\/tr>\n
Product number<\/td>\nL07<\/td>\nE07<\/td>\nE077<\/td>\nR44<\/td>\n<\/tr>\n
regulatory status (EU)<\/td>\nRUO<\/td>\nIVD<\/td>\nIVD<\/td>\n\n

IVD<\/p>\n<\/td>\n<\/tr>\n

Reference material<\/td>\nNIBSC 97\/594<\/td>\nNIBSC 97\/594<\/td>\nNIBSC 97\/594<\/td>\nNIBSC 97\/594<\/td>\n<\/tr>\n
Incubation period<\/td>\n4 h<\/td>\n1,75 h<\/td>\n1,75 h<\/td>\n15 h<\/td>\n<\/tr>\n
Antibody<\/td>\nRabbit<\/td>\nMouse<\/td>\nMouse<\/td>\nRabbit<\/td>\n<\/tr>\n
Calibrator<\/td>\nrecom. Leptin<\/td>\nrecom. Leptin<\/td>\nrecom. Leptin<\/td>\nrecom. Leptin<\/td>\n<\/tr>\n
Assay Range
\n[\u00b5g\/L]<\/td>\n		1 –
\n120<\/td>\n		0,25 – 100<\/td>\n0,014 – 50<\/td>\n0,1 – 64<\/td>\n<\/tr>\n
Sample matrix<\/td>\nSerum\/ Plasma<\/td>\nSerum\/ Plasma<\/td>\nSerum\/ Plasma<\/td>\n\n

Serum\/ Plasma<\/p>\n<\/td>\n<\/tr>\n

Sample dilution<\/td>\n1:20<\/td>\nun-
\ndiluted<\/td>\n		1:10<\/td>\nun-
\ndiluted<\/td>\n<\/tr>\n
analyt. Sensitivity
\n[\u00b5g\/L]<\/td>\n		0,01<\/td>\n< 0.25<\/td>\n0,014<\/td>\n0,1<\/td>\n<\/tr>\n
Intra-\/Interassay Variance [%]<\/td>\n<10<\/td>\n<15<\/td>\n<10<\/td>\n<10<\/td>\n<\/tr>\n
Reference values<\/td>\nBlum WF, Juul A; Reference ranges of serum leptin, In: Leptin- the voice of adipose tissue, Blum WF et al. eds. Johann Ambrosius Verlag, Heidelberg, 1997
\n<\/a><\/p>\n
<\/div>\n<\/td>\n<\/tr>\n
Package insert<\/td>\n\"PDF<\/a><\/td>\n\"PDF<\/a><\/td>\n\"PDF<\/a><\/td>\n\"PDF<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"excerpt":{"rendered":"

Leptin is a hormone of adipose tissue and is mainly synthesized by adipocytes. It consists of 167 amino acids and has a molecular weight of 18.64 kDa. Leptin is involved in the regulation of food intake. The concentration of leptin in the circulation is measured in ... Read More<\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"_links":{"self":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages\/3131"}],"collection":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/comments?post=3131"}],"version-history":[{"count":22,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages\/3131\/revisions"}],"predecessor-version":[{"id":4856,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages\/3131\/revisions\/4856"}],"wp:attachment":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/media?parent=3131"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}