{"id":3094,"date":"2017-04-19T14:21:39","date_gmt":"2017-04-19T12:21:39","guid":{"rendered":"https:\/\/mediagnost.de\/?page_id=3094"},"modified":"2023-11-13T10:45:44","modified_gmt":"2023-11-13T09:45:44","slug":"igfbp-1-human-2","status":"publish","type":"page","link":"https:\/\/mediagnost.de\/en\/igfbp-1-human-2\/","title":{"rendered":"IGFBP-1 human"},"content":{"rendered":"

IGFBP-1 (insulin-like growth factor binding protein 1) <\/a>is a component of the IGF system and one of seven binding proteins that bind IGF-I with high affinity. It has a molecular mass of 25.3 kDa, contains 18 cysteines, and is postranslationally modified by phosphorylation, affecting IGF-I affinity . IGFBP-1 expression appears to be inhibited by insulin, whereas cortisol and glucagon stimulate its production. Also an influence on Preeclampsia<\/a> is discussed in the literature.
\n<\/span><\/p>\n

The IGFBP-1 ELISA (insulin-like growth factor binding protein -1) reliably determines the concentration of human IGFBP-1 in serum, plasma and amniotic fluid. <\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
IGFBP-1-<\/span> ELISA<\/span>
\n<\/strong><\/td>\n<\/tr>\n
Product number<\/td>\n\n

E01<\/p>\n<\/td>\n<\/tr>\n

Regulatory status<\/td>\n\n

IVD<\/p>\n<\/td>\n<\/tr>\n

Incubation period<\/td>\n1,75 h<\/td>\n<\/tr>\n
Antibody<\/td>\nMouse<\/td>\n<\/tr>\n
Calibrator<\/td>\nnative human IGFBP-1<\/td>\n<\/tr>\n
Assay Range
\n[\u00b5g\/L]<\/td>\n		0 – 128<\/td>\n<\/tr>\n
Samples<\/td>\n\n

Serum
\nEDTA \/ Heparin Plasma<\/p>\n<\/td>\n<\/tr>\n

Sample dilution<\/td>\n1:16<\/td>\n<\/tr>\n
analyt. Sensitivity
\n[\u00b5g\/L]<\/td>\n		< 0.1<\/td>\n<\/tr>\n
Intra-\/Interassay Variance [%]<\/td>\n< 10<\/td>\n<\/tr>\n
Package insert<\/td>\n\"PDF<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"excerpt":{"rendered":"

IGFBP-1 (insulin-like growth factor binding protein 1) is a component of the IGF system and one of seven binding proteins that bind IGF-I with high affinity. It has a molecular mass of 25.3 kDa, contains 18 cysteines, and is postranslationally modified by phosphorylation, increasing IGF-I affinity ... Read More<\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"acf":[],"_links":{"self":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages\/3094"}],"collection":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/comments?post=3094"}],"version-history":[{"count":7,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages\/3094\/revisions"}],"predecessor-version":[{"id":4824,"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/pages\/3094\/revisions\/4824"}],"wp:attachment":[{"href":"https:\/\/mediagnost.de\/en\/wp-json\/wp\/v2\/media?parent=3094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}