Progranulin is an 88kDa protein and is established as a marker for frontotemporal dementia (FTD); decreased serum progranulin concentrations occur in approximately 5-10% of patients with FTD. In contrast, an increase in serum progranulin levels has been demonstrated in type 2 diabetics. Progranulin seems to reflect the distribution of adipose tissue and could be a biomarker for the amount of visceral adipose tissue.
The Mediagnost Progranulin ELISA is an assay with good reproducibility that detects progranulin and not granulins with high specificity.
| Progranulin ELISA |
|
| Product number |
E103 |
| Regulatory status |
RUO |
| Reference material | recombinant progranulin |
| Incubation period | 2h |
| Antibody | Mouse |
| Standard | recombinant progranulin |
| Assay Range [µg/L] |
0,018 – 103 |
| Samples |
Serum |
| Sample dilution | 1:41 |
| analyt. Sensitivity [µg/L] |
0,018 |
| Intra-/Interassay Variance [%] | <10 |
| Package insert |  |
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